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Nursing Ethics
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Ethical Considerations for Nurses in Clinical Trials

Kathleen Oberle

University of Calgary, Calgary, Alberta, Canada, oberle{at}ucalgary.ca

Marion Allen

University of Alberta, Edmonton, Alberta, Canada

Ethical issues arise for nurses involved in all phases of clinical trials regardless of whether they are caregivers, research nurses, trial co-ordinators or principal investigators. Potential problem areas centre on nurses’ moral obligation related to methodological issues as well as the notions of beneficence/non-maleficence and autonomy. These ethical concerns can be highly upsetting to nurses if they are not addressed, so it is imperative that they are discussed fully prior to the initiation of a trial. Failure to resolve these issues can place both the conduct and the results of research in jeopardy.

Key Words: beneficience/non-maleficence • clinical trials • ethical issues • moral obligation • therapeutic obligation

Nursing Ethics, Vol. 13, No. 2, 180-186 (2006)
DOI: 10.1191/0969733006ne836oa
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